HomeIndiaCovid infection may impact...

Covid infection may impact semen quality in men: AIIMS study


NEW DELHI: Infection with the SARS-CoV-2 virus may negatively impact semen quality, according to a study on 30 males conducted by researchers at the All India Institute of Medical Sciences.

The team led by researchers at AIIMS Patna noted that COVID-19 can lead to multiorgan damage through the angiotensin-converting enzyme-2 receptor (ACE2), abundant in testicular tissue.

ACE2 acts as the receptor for the SARS-CoV-2 spike protein, through which the virus gains entry into the host cells.

However, little information is available regarding the shedding of SARS-CoV-2 in semen — the thick, white fluid that contains sperm — and its impact on sperm formation and fertility potential.

The study, published in the Cureus Journal of Medical Science, investigated the presence of SARS-CoV-2 in the semen of COVID-19 males.

The researchers also analysed the effect of the disease on semen quality and sperm DNA fragmentation index, which reflects the integrity of and the damage to the DNA, thereby detecting potential sperm damage.

Thirty COVID-19 male patients aged 19-45 registered to AIIMS Patna hospital participated in the study between October 2020 and April 2021.

“We conducted a real-time reverse transcriptase test on all the semen samples. Detailed semen analysis, including the sperm DNA fragmentation index, was done at first sampling that is during COVID-19,” the authors of the study said.

“After 74 days of the first sampling, we obtained the second sampling and repeated all the tests,” they said.

The study, including researchers from AIIMS Managalagiri and AIIMS New Delhi, found that all semen samples collected in the first and second sampling tested with real-time reverse transcription-polymerase chain reaction (RT-PCR) were negative for SARS-CoV-2.

In the first sampling, semen volume, vitality, total motility, sperm concentration, and total sperm count were significantly lower, the researchers said.

In contrast, semen agglutination or formation of sperm heaps, head defect, DNA fragmentation index, liquefaction time, semen viscosity, and leukocytes or white blood cells, were increased.

Liquefaction time is a measure of the time it takes for the semen to turn into liquid while viscosity is the thickness of the seminal fluid.

These results were reversed at the second sampling but not to the optimum level, according to the resaerchers.

The findings were statistically significant suggesting “COVID-19 negatively affects semen parameters, including sperm DNA fragmentation index,” the authors noted.

“Although we could not find SARS-CoV-2 in the semen, the semen quality remained poor until the second sampling,” they said.

The researchers noted that assisted reproductive technology (ART) clinics and sperm banking facilities should consider assessing the semen of COVID-19 infected males.

ART includes all fertility treatments in which either eggs or embryos are handled.

These clinics should exclude men with a positive history of SARS-CoV-2 until their semen quality returns to normal, the researchers added. (PTI)

Most Popular

LEAVE A REPLY

Please enter your comment!
Please enter your name here

More from Author

Study Narrows Down Long COVID Symptoms To Just 7

Long COVID, the medical mystery that continues to boggle the minds...

Depressed Young Adults Likely To Develop Heart Disease And Vice-Versa

Young adults or people in the 18-25 age group are at...

More Women Are Dying From ‘Preventable’ Cervical Cancer: Study

More older women have succumbed to cervical cancer in recent years,...

Read Now

Study Narrows Down Long COVID Symptoms To Just 7

Long COVID, the medical mystery that continues to boggle the minds of scientists and medical researchers, comes with an extensive list of symptoms. But a new study narrowed down the 47 reported symptoms to just seven. Published in the journal Open Forum Infectious Disease, the study by the...

Depressed Young Adults Likely To Develop Heart Disease And Vice-Versa

Young adults or people in the 18-25 age group are at risk of suffering two serious health issues: depression and heart disease. A new study found a “two-way street” relationship between depression and an increased risk of cardiovascular disease (CVD) in younger adults. According to the Johns Hopkins Medicine...

Obesity Found To Cause Alzheimer’s-Like Condition; Weight Loss Reduces Risk

Obese people are at risk of suffering a condition similar to Alzheimer’s disease. But this can be countered by healthy weight loss. A McGill University study published Tuesday in the Journal of Alzheimer’s Disease presented a correlation between obesity-associated neurodegeneration and Alzheimer’s. Using data from the Alzheimer’s Disease Neuroimaging...

More Women Are Dying From ‘Preventable’ Cervical Cancer: Study

More older women have succumbed to cervical cancer in recent years, even though the condition is  preventable. A new study from the University of California, Davis found a spike in older women suffering from late-stage cancer. And since they develop the disease at an older age, their chances...

Befitting response given to every ‘misadventure’ from LoC to LAC: President Murmu

NEW DELHI: President Droupadi Murmu on Tuesday said the government has been laying constant emphasis on modernising the military as it firmly believes...

NIA files chargesheet against IS operative for conspiring to recruit youth for terror activities in India

NEW DELHI: The National Investigation Agency (NIA) on Tuesday filed a chargesheet against an accused in a case related to a conspiracy hatched...

First-Of-Its-Kind $1 Glove Can Detect Fetal Positions To Aid Precarious Births

An ingenious innovation of a smart glove that costs less than $1 has been created with the aim to aid clinicians during birth. The study, published in the open-access journal Frontiers in Global Women’s Health, engineered the device to help healthcare staff in finding the fetal position and the...

Study Finds Threatened Sharks Being Served In Fish Fillets

The ultimate British dish--fish and chips--have takers all over the world. However, the fish served in the dish might actually be an endangered shark species.A recent study, published in the journal Food Control, found shocking samples of endangered shark species in several fish filets served at more...

Coffee With Milk Has Strong Anti-Inflammatory Effect: Study

An ardent proponent of the benefits of black coffee? You might have to change allegiance, as a new study has found coffee with milk has synergistic properties that increase its anti-inflammatory effect.The study, published in the Journal of Agricultural and Food Chemistry, found that the antioxidants from coffee combined...

All-Party Meet ahead of Budget Session held

STATE TIMES NEWS New Delhi: The government on...

This Is How Many Adult Americans Are Addicted To Junk Food

More older adults in the United States have become addicted to processed food, according to a recent University of Michigan poll. The school’s National Poll on Health Aging presented alarming findings in its January-February 2023 issue, saying that based on the latest data, 1 in 8 adults over...

Bengaluru colleges ban use of ChatGPT, the AI agent that writes assignments

At a time when the use of AI tools has grown exponentially, plagiarism is becoming an increasingly pressing issue for universities. RV University in Bengaluru has recently taken steps to curb the use of such tools, particularly ChatGPT, by banning it altogether. The move is supported by...