HomeScience and TechnologyHealth'Changes In Almost All...

‘Changes In Almost All Regions Of Brain’

A comprehensive study has found clear biomarkers in the MRI scans of children diagnosed with attention deficit/hyperactivity disorder (ADHD).

The findings of the study were presented recently at the annual meeting of the Radiological Society of North America (RSNA). The study also found the potential use of neuroimaging machine learning in the diagnosis, treatment planning, and surveillance of the disorder.

ADHD, one of the most prevalent neurodevelopmental disorders in childhood, affects about 6 million American children between the ages of 3 and 17 years, according to SciTechDaily. Symptoms of the disorder include trouble paying attention and controlling impulsive behaviors or being overly active. The disorder is diagnosed by a child’s caregiver, which includes a checklist to rate the presence of ADHD symptoms.

“There’s a need for a more objective methodology for a more efficient and reliable diagnosis,” study co-author Huang Lin, a post-graduate researcher at the Yale School of Medicine in New Haven, Connecticut, said, the outlet reported. “ADHD symptoms are often undiagnosed or misdiagnosed because the evaluation is subjective.”

For the analysis, researchers used MRI data from the Adolescent Brain Cognitive Development (ABCD) study, the largest long-term study of brain development and child health in the United States. From the ABCD study, data from 7,805 children aged 9-10 years, including 1,798 diagnosed with ADHD children was analyzed.

“The demographics of our group mirror the U.S. population, making our results clinically applicable to the general population,” Lin said, as per the outlet.

Following analysis, the association of ADHD with neuroimaging metrics, including brain volume, surface area, white matter integrity, and functional connectivity, was studied.

“We found changes in almost all the regions of the brain we investigated,” Lin noted. “The pervasiveness throughout the whole brain was surprising since many prior studies have identified changes in selective regions of the brain.”

Abnormal connectivity in the brain networks involved in memory and auditory processing, a thinning of the brain cortex, and pronounced white matter microstructural changes were found in ADHD patients.

“Our study underscores that ADHD is a neurological disorder with neuro-structural and functional manifestations in the brain, not just a purely externalized behavior syndrome,” Lin said.

“At times when a clinical diagnosis is in doubt, objective brain MRI scans can help to clearly identify affected children. Objective MRI biomarkers can be used for decision-making in ADHD diagnosis, treatment planning, and treatment monitoring,” Lin further added.

The researcher is also confident their MRI data was significant enough to be used as input for machine learning models to predict an ADHD diagnosis. Machine learning will be able to analyze large amounts of MRI data.

A separate study found that caffeine could be a possible treatment for some of the symptoms of ADHD. “The therapeutic arsenal for alleviating ADHD is limited, and there is a certain degree of controversy around the use of some types of medications and stimulants, especially during childhood and adolescence,” Javier Vázquez of Universitat Oberta de Catalunya (UOC), one of the new study’s main authors, said in the UOC news release. “That’s why it’s useful to study the efficacy of other substances, such as caffeine.”

Most Popular


Please enter your comment!
Please enter your name here

More from Author

Read Now

Rise In Maternal Mortality Prompts Proposal For Frequent Blood Pressure Monitoring During, After Pregnancy

Pregnant women in the U.S. are being obliged to have their blood pressure screened and monitored during and after their pregnancy in response to the rise in maternal mortality in the country. On Tuesday, the U.S. Preventive Services Task Force issued a draft recommendation proposing a mandatory screening...

Mysterious Meningitis Kills At Least 35 In Mexico Amid Outbreak

Northern Mexico is still grappling with a mysterious meningitis outbreak after state officials reported another fatality due to the condition on Monday, bringing the total number of deaths to 35. Specific details about the latest death amid the outbreak weren’t immediately available, but health authorities in Mexico’s rural...

Vitamin D Effectively Prevents Type 2 Diabetes In 3 Clinical Trials

Pre-diabetic people could turn to vitamin D supplements for help in preventing their condition from progressing to type 2 diabetes. This is what scientists discovered after conducting clinical trials with the supplements. Researchers found after three randomized clinical trials that vitamin D supplements are modestly effective in lowering the...

Interests of poor at centre of every budget presented by BJP Govt: Modi

STATE TIMES NEWS New Delhi: Prime Minister Narendra...

BJP wave sweeping across Meghalaya: Chugh

STATE TIMES NEWS MEGHALAYA: BJP National General Secretary...

JEE-Main result: 20 candidates score perfect 100, NTA score of 50 candidates withheld

STATE TIMES NEWS New Delhi: Twenty candidates have scored perfect 100 in engineering entrance exam JEE-Main’s January edition, the National Testing Agency (NTA) announced...

No. of medical colleges in India has gone up to 654 from 387 since 2014: Govt

NEW DELHI: There has been a 69-per cent increase in the number of medical colleges in the country, from 387 before 2014 to...

Doctors stage protest demanding postponement of NEET-PG exam

NEW DELHI: A group of doctors, including NEET-PG aspirants, held a protest at the Jantar Mantar Road here on Tuesday, demanding the postponement...

AgustaWestland chopper scam: SC denies bail to alleged middleman Christian Michel James

NEW DELHI: The Supreme Court on Tuesday denied bail to Christian Michel James, an alleged middlemen in AgustaWestland chopper scam cases, who is...

India can be superpower in defence manufacturing: General Chauhan

PUNE: Lauding the private sector contribution in defence manufacturing, Chief of Defence Staff (CDS) General Anil Chauhan on Tuesday said India has the...

India hits out at Pakistan for raking up Kashmir issue at UN

UNITED NATIONS: India has slammed Pakistan for raking up the Kashmir issue in the United Nations, saying Islamabad harbours a deep sense of...

There’s temptation to play three spinners but you never know with Nagpur pitch: KL Rahul

NAGPUR: India’s Test vice-captain KL Rahul feels it’s never easy to predict the nature of a track but there is a “temptation” to...