A drug that destroys the outer membrane of certain bacteria could work against infections when antibiotics fail. It successfully killed a bacterial species resistant to most treatments and is currently being tested for safety in humans.
Antibiotic resistance is a major threat to global health. In 2019, it killed about 1.3 million people worldwide and contributed to almost 4 million additional deaths. Of particular concern is Carbapenem-resistant Acinetobacter baumannii (CRAB), which the World Health Organization classifies as a priority 1 critical pathogen due to a…